| 名稱 | 重組蛋白Recombinant Human IL-1α |
| 型號 | |
| 更新時間 | 2023-09-25 |
| 特點 | IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells.} |
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- 詳細(xì)內(nèi)容
一.產(chǎn)品名稱：Recombinant Human IL-1β
二.Catalog Number:200-01B
三.Synonyms:
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
四.Description:
IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1β is a 17.3 kDa protein containing 153 amino acid residues.
五.AA Sequence:
APVRSLNCTL RDSKSLVM SGPYELKALH LQGQDMEV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS
六.Source:E.coli
七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
八.Biological Activity:
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by murine D10S cells is ≤ 1.0 pg/ml, corresponding to a specific activity of ≥ 1 x 109 units/mg.
九.Cross Reactivity:
Frog, Monkey, Mouse, Rabbit, Rat, Sheep, Human, Mouse + Chicken, Cow, Human + Rat, Pig
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電話/傳真：13366128764
手機(jī)：15311648455
地址：北京市海淀區(qū)廂黃旗2號樓1層4-179室